Dose Escalation, Randomized Controlled Trial to Evaluate the Safety, Immunogenicity and Efficacy of Intravenously Administered Attenuated Plasmodium Falciparum Sporozoite Vaccine (PfSPZ Vaccine) in Tanzanian Adults
PHASE1
This trial will evaluate whether relatively non-immune populations in endem...
Status
Completed
Location
Bagamoyo Research and Training Center, Ifakara Health Institute, Kingani Estate, PO Box 74
Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B...
PHASE1
Background:
\- Malaria is a severe infection caused by a parasite. People ...
Status
Completed
Location
National Institutes of Health Clinical Center, 9000 Rockville Pike